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Drawback Of Ball Milling Technique

Drawback Of Ball Milling Technique

Milling is a common diminution technique in the pharmaceutical industry to improve the performance of drugs, including their dissolution rates 7,8.However, the major drawback of this process is the possible mechanical activation of the milled drug and subsequent introduction of process induced disorder .Process induced disorder in this context is defined as a pre-amorphous solid state.

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